“pan-PI3K inhibitor CLR457”的概念、定义、翻译、参考文献-科学参考

单词	pan-PI3K inhibitor CLR457
释义	pan-PI3K inhibitor CLR457 An orally bioavailable pan inhibitor of phosphatidylinositol-3-kinase (PI3K), with potential antineoplastic activity. Upon oral administration, pan-PI3K inhibitor CLR457 inhibits all of the PI3K kinase isoforms, which may result in apoptosis and growth inhibition in tumor cells overexpressing PI3K. Activation of the PI3K pathway promotes cell growth, survival, and resistance to both chemotherapy and radiotherapy.
随便看	BBB BBBD BBIC BBR 2778 BBR 3464 BC-819 plasmid/polyethylenimine complex B cell B-cell acute lymphoblastic leukemia B-cell leukemia/lymphoma 2 protein B-cell lymphoma BCG BCG solution BCG vaccine BCL2 bcl-2 antisense oligodeoxynucleotide G3139 Bcl-2 inhibitor BCL201 BCMA-specific CAR-expressing T lymphocytes BCNU BCOP bcr-abl (b2a2)-derived peptide vaccine bcr-abl (b3a2)-derived peptide vaccine BCR-ABL fusion gene BCR-ABL fusion protein bcr-abl p210-b3a2 breakpoint-derived multipeptide vaccine bcr-abl peptide vaccine

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