“anti-GnRH vaccine PEP223”的概念、定义、翻译、参考文献-科学参考

A peptide vaccine derived from the synthetic peptide pyroEHWSYGLRPG, corresponding to amino acids 22-31 of mouse gonadotropin releasing hormone (GnRH), with potential immunocastration activity. PEP223 is dimerized and contains a D-lysine (k) substitution at position 6 (pyroEHWSYkLRPG) to increase its immunogenicity. Anti-GnRH vaccine PEP223 may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against GnRH, neutralizing its activity. In turn, testosterone production and tumor cell growth may be inhibited in testosterone-sensitive tumors. Check for active clinical trialsusing this agent.

单词	anti-GnRH vaccine PEP223
释义	anti-GnRH vaccine PEP223 A peptide vaccine derived from the synthetic peptide pyroEHWSYGLRPG, corresponding to amino acids 22-31 of mouse gonadotropin releasing hormone (GnRH), with potential immunocastration activity. PEP223 is dimerized and contains a D-lysine (k) substitution at position 6 (pyroEHWSYkLRPG) to increase its immunogenicity. Anti-GnRH vaccine PEP223 may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against GnRH, neutralizing its activity. In turn, testosterone production and tumor cell growth may be inhibited in testosterone-sensitive tumors. Check for active clinical trialsusing this agent.
随便看	resiquimod resiquimod resiquimod topical gel resistant cancer resistant starch resminostat Resolving power resolving power Resonance Resonance resorption resource partitioning Respbid respiration respirator respiratory disease respiratory syncytial virus respiratory system respiratory therapist respiratory therapy respiratory tract respite care response Response Evaluation Criteria In Solid Tumors response rate