The agent paclitaxel linked to a biodegradable, water-soluble polyglutamate polymer with antineoplastic properties. The polyglutamate residue increases the water solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. Paclitaxel promotes microtubule assembly and prevents microtubule depolymerization, thus interfering with normal mitosis. or A form of the anticancer drug paclitaxel used to treat breast cancer, ovarian cancer, and AIDS-related Kaposi sarcoma. It is also used with another drug to treat non-small cell lung cancer. Paclitaxel is mixed with very tiny particles of a substance that makes it easier to dissolve in water. This allows higher doses of paclitaxel to be given. It is a type of antimitotic agent.