A biodegradable poly(ethylene glycol)-poly(D,L-lactide) copolymer miceller nanoparticle-entrapped formulation of paclitaxel with antineoplastic activity. Paclitaxel promotes microtubule assembly and prevents depolymerization, thus interfering with normal mitosis. The copolymer residue increases the water-solubility of paclitaxel and allows delivery of higher doses than those achievable with paclitaxel alone. or An abbreviation for a chemotherapy combination used to treat multiple myeloma. It includes the drugs bortezomib, doxorubicin (Adriamycin), and dexamethasone. Also called PAD.